Molecular beam epitaxy, cyangwa MBE, ni tekinike nshya yo gukura amafirime meza yo mu rwego rwo hejuru ya kristu kuri kristu. Mugihe cya ultra-high vacuum conditions, ukoresheje amashyiga ashyushye afite ibikoresho byose bisabwa kandi bikabyara amavuta, binyuze mumyobo yakozwe nyuma yo kwegeranya urumuri rwa atome cyangwa molekile, gutera inshinge zubushyuhe bukwiye bwa substrate imwe, kugenzura urumuri rwa molekile kugeza substrate yogusikana icyarimwe, irashobora gukora molekile cyangwa atome murwego rwo guhuza kristu kugirango ikore firime yoroheje kuri substrate "gukura".

Kugirango imikorere isanzwe yibikoresho bya MBE, isuku nyinshi, umuvuduko muke hamwe na azote isukuye cyane ya azote isabwa guhora kandi ijyanwa mucyumba gikonjesha ibikoresho. Muri rusange, ikigega gitanga azote yuzuye gifite umuvuduko usohoka hagati ya 0.3MPa na 0.8MPa. Azote y'amazi kuri -196 ℃ ihinduka umwuka mubi muri azote mugihe cyo gutwara imiyoboro. Amazi azote namara gazi ya gazi ya 1: 700 imaze guhumeka mumazi, bizatwara umwanya munini wa azote yuzuye kandi bigabanye umuvuduko usanzwe kumpera yumuyoboro wa azote. Byongeye kandi, mu kigega cyo kubika azote yuzuye, hashobora kuba imyanda itarasukurwa. Mu miyoboro ya azote yuzuye, kubaho umwuka utose bizanatuma habaho urubura. Niba ibyo byanduye bisohotse mubikoresho, bizangiza ibyangiritse bitateganijwe.

Kubwibyo, azote yuzuye mumazi yo kubika hanze ijyanwa mubikoresho bya MBE mumahugurwa adafite ivumbi hamwe nubushobozi buhanitse, butajegajega kandi busukuye, hamwe numuvuduko muke, nta azote, nta mwanda, amasaha 24 ntahagarikwa, ubwo buryo bwo kugenzura ubwikorezi ni ibicuruzwa byujuje ibyangombwa.